The greatest picks outside of lane to counter 诺克萨斯之手 include 复仇之矛, 探险家, and 祖安花火. These champs are all good at countering 诺克萨斯之手 with high win rates over 61%. Even if these 诺克萨斯之手 counter picks are not picked in your lane, it's not a good idea to choose him into one of these matchups. They will very likely crush 诺克萨斯之手.
Yet, if the opposite team choses either 机械公敌 or 爆破鬼才, you should strongly think about picking him, as he easily dominates these champs with win rates over 53% against each ofthem.